Sepsis, Inflamació i Seguretat del Malalt Crític (SIS)

INFECCIÓ, IMMUNITAT I MEDI AMBIENT
OBJECTIUS

El grup SIS està constituït per un nucli de 10 investigadors doctors y 20 investigadors clínics multidisciplinari que coincideixen en interessos i línies de recerca i que estan desenvolupant conjuntament nous projectes en l’àmbit de la sèpsia, la inflamació, la seguretat en el malalt crític i anàlisis de dades en salut (BIG-DATA i Machine Learning).

RESPONSABLES
  • Dra. María Bodí

  • Dr. Alejandro Rodriguez Oviedo

  • Presentació
  • Línies de recerca
  • Membres del grup
  • Transferència
  • Publicacions
  • Projectes
  • Difusió
  • Contacte

María Bodí i Alejandro Rodríguez (responsables del grup) són membres del CIBERes (ISCIII) node 14 (IP Dr. Antoni Torres). El grup s’estructura al voltant d’un investigador responsable (María Bodí) que és professora associada de la URV, Cap del Servei de Medicina Intensiva de l’HJ23 i Coordinadora Territorial de Trasplantaments de la província de Tarragona i  Alejandro Rodriguez, també professor associat de la URV i Coordinador Nacional del registre de Grip Greu /COVID-19 de la SEMICYUC.

Al llarg d’aquests darrers anys com a Grup de Recerca Consolidat (AGAUR) s’han pogut consolidar les diferents línies de recerca del Grup a través un gran número de projectes competitius nacionals i internacionals, i s’ha consolidat una línea d’investigació en dades de salut amb la incorporació de 4 científics de dades. El grup SIS té una elevada producció científica amb més de 70 punts de factor d’impacte per any.

  • Sèpsia: Epidemiologia general i molecular
  • Diagnòstic, prevenció i tractament
  • Inflamació, hipòxia i alteracions macro i microcirculatorias
  • Seguretat del pacient crític
  • Donació i Trasplantament
  • Sistemes TIC, qualitat, seguretat de l’pacient crític
  • Anàlisi de dades en salut, Big Data i Machine Learning

  • ICU-DaMa: (Intesive care Data Management) iDEPOT 102487

  • AASTRE: (Análisis Aleatorios de Seguridad en Tiempo Real) T-0629-2012

    Año

    Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data toDetermine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection

    Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP,Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, BooyR, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C,Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P,Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, IslamQT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E,Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, ManabeT, Metan G, Mickiene A, Mikić D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M,Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skręt-Magierło J, Somer A,Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P;PRIDE Consortium Investigators , Nguyen-Van-Tam JS

    J Infect Dis

    DOI: 10.1093/infdis/jiz152

    Associated risk factors and outcomes of acute kidney injury in severe trauma: Results from the Spanish trauma ICU registry (RETRAUCI)

    Mario Chico-Fernández, Jesús Abelardo Barea-Mendoza , Txoan Ormazabal-Zabala, Gerard Moreno-Muñoz , Diego Pastor-Marcos et al.,
    Anaesthesia Critical Care & Pain Medicine. 2020 Aug;39(4):503-506.

    DOI: 10.1016/j.accpm.2019.11.003

    Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia

    Gaudet A, Martin-Loeches I, Povoa P, Rodriguez A, Salluh J, Duhamel A, Nseir S
    Ann Intensive Care. 2020 Aug 3;10(1):101

    DOI: 10.1186/s13613-020-00721-4

    Major Adverse Cardiovascular Events During Invasive Pneumococcal Disease are Serotype Dependent

    Africano HF, Serrano-Mayorga CC, Ramirez-Valbuena PC, Bustos IG, Bastidas A, Vargas HA, Gómez S, Rodriguez A, Orihuela CJ, Reyes LF.
    2020 Sep 22 [Epub ahead of print]. Clin Infect Dis.

    DOI: 10.1093/cid/ciaa1427

    The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: Data from the multinational SMARRT Study

    Roberts JA, Joynt G, Lee A, Choi G, Bellomo R, Kanji S, Mudaliar MY, Peake SL, Stephens D, Taccone FS, Ulldemolins M, Valkonen MM, Agbeve J, Baptista JP, Bekos V, Boidin C, Brinkmann A, Buizen L, Castro P, Cole CL, Creteur J, De Waele JJ, Deans R, Eastwood GM, Escobar L, Gomersall C, Gresham R, Jamal JA, Kluge S, König C, Koulouras VP, Lassig-Smith M, Laterre PF, Lei K, Leung P, Lefrant JY, Llauradó-Serra M, Martin-Loeches I, Mat Nor MB, Ostermann M, Parker SL, Rello J, Roberts DM, Roberts MS, Richards B, Rodríguez A, Roehr AC, Roger C, Seoane L, Sinnollareddy M, Sousa E, Soy D, Spring A, Starr T, Thomas J, Turnidge J, Wallis SC, Williams T, Wittebole X, Zikou XT, Paul S, Lipman J.
    2020 Mar 9 [Epub ahead of print] Clin Infect Dis.

    DOI: 10.1093/cid/ciaa224

    Update of the treatment of nosocomial pneumonia in the ICU

    Zaragoza R, Vidal-Cortés P, Aguilar G, Borges M, Diaz E, Ferrer R, Maseda E, Nieto M, Nuvials FX, Ramirez P, Rodriguez A, Soriano C, Veganzones J, Martín-Loeches I.
    Crit Care. 2020 Jun 29;24(1):383.

    DOI: 10.1186/s13054-020-03091-2

    Lower Respiratory Tract Infection and Short-Term Outcome in Patients With Acute Respiratory Distress Syndrome

    Zampieri FG, Póvoa P, Salluh JI, Rodriguez A, Valade S, Andrade Gomes J, Reignier J, Molinos E, Almirall J, Boussekey N, Socias L, Ramirez P, Viana WN, Rouzé A, Nseir S, Martin-Loeches I.
    J Intensive Care Med. 2020 Jun;35(6):588-594.

    DOI: 10.1177/0885066618772498

    Impact of difficult sedation on the management and outcome of critically ill patients

    Gil Castillejos D, Rubio ML, Ferre C, de Gracia MLÁ, Bodí M, Sandiumenge A.
    Nurs Crit Care. 2020 Sep 24.

    DOI: 10.1111/nicc.12558

    Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia

    Villafuerte D, Aliberti S, Soni NJ, Faverio P, Marcos PJ, Wunderink RG, Rodriguez A, Sibila O, Sanz F, Martin-Loeches I, Menzella F, Reyes LF, Jankovic M, Spielmanns M, Restrepo MI.
    Respirology. 2020 May;25(5):543-551

    DOI: 10.1111/resp.13663

    Serum levels of neutrophil Gelatinase associated Lipocalin (NGAL) predicts hemodialysis after coronary angiography in high risk patients with acute coronary syndrome

    Reyes LF, Severiche-Bueno DF, Bustamante CA, Murillo S, Soni NJ, Poveda M, Gomez E, Buitrago R, Rodriguez A.
    BMC Nephrol. 2020 Apr 22;21(1):143.

    DOI: 10.1186/s12882-020-01799-5

    Influenza management with new therapies

    O’Sullivan S, Torres A, Rodriguez A, Martin-Loeches I.
    Curr Opin Pulm Med. 2020 May;26(3):215-221.

    DOI: 10.1097/MCP.0000000000000667

    Ceftolozane and tazobactam for the treatment of hospital acquired pneumonia

    Martin-Loeches I, Bisanti A, Diaz E, Rodriguez A.
    Expert Rev Anti Infect Ther. 2020 Dec;18(12):1177-1185.

    DOI: 10.1080/14787210.2020.1794816

    Impact of Chronic Obstructive Pulmonary Disease on Incidence, Microbiology and Outcome of Ventilator-Associated Lower Respiratory Tract Infections

    Rouzé A, Boddaert P, Martin-Loeches I, Povoa P, Rodriguez A, Ramdane N, Salluh J, Houard M, Nseir S.
    Microorganisms. 2020 Jan 23;8(2):165.

    DOI: 10.3390/microorganisms8020165

    Online education about end-of-life care and the donation process after brain death and circulatory death. Can we influence perception and attitudes in critical care doctors? A prospective study

    Sandiumenge A, Lomero Martinez MDM, Sánchez Ibáñez J, Seoane Pillado T, Montaña-Carreras X, Molina-Gomez JD, Llauradó-Serra M, Dominguez-Gil B, Masnou N, Bodi M, Pont T.
    Transpl Int. 2020 Nov;33(11):1529-1540.

    DOI: 10.1111/tri.13728

    Positive-pressure needleless connectors did not increase rates of catheter hub colonization respecting the use of neutral-pressure needleless connectors in a prospective randomized trial

    Delgado M, Capdevila JA, Sauca G, Méndez J, Rodriguez A, Yébenes JC
    Enferm Infecc Microbiol Clin (Engl Ed). 2020 Mar;38(3):119-122. English, Spanish.

    DOI: 10.1016/j.eimc.2019.07.012

    ADENI-UCI Study: Analysis of non-income decisions in ICU as a measure of limitation of life support treatments.

    Escudero-Acha P, Leizaola O, Lázaro N, Cordero M, Cossío AM, Ballesteros D, Recena P, Tizón AI, Palomo M, Del Campo MM, Freita S, Duerto J, Bilbao NM, Vidal B, González-Romero D, Diaz-Dominguez F, Revuelto J, Blasco ML, Domezain M, de la Concepción Pavía-Pesquera M, Rubio O, Estella A, Pobo A, Gomez-Acebo I, González-Castro A;
    Med Intensiva (Engl Ed). Dec 29:S0210-5691(20)30342-9. English, Spanish.

    DOI: 10.1016/j.medin.2020.11.003

    Severe infection due to the SARS-CoV-2 coronavirus: Experience of a tertiary hospital with COVID-19 patients during the 2020 pandemic

    Rodríguez A, Moreno G, Gómez J, Carbonell R, Picó-Plana E, Benavent Bofill C, Sánchez Parrilla R, Trefler S, Esteve Pitarch E, Canadell L, Teixido X, Claverias L, Bodí M.
    Med Intensiva (Engl Ed). 2020 Dec;44(9):525-533. English, Spanish.

    DOI: 10.1016/j.medin.2020.05.018

    Comment to «In reply tothe question: Are we really playing together in the same team?»

    Lomero-Martínez MM, Jiménez-Herrera MF, Bodí-Saera MA, Llaurado-Serra M,Masnou-Burrallo N, Oliver-Juan E, Sandiumenge-Camps A
    EnfermIntensiva
    DOI: 10.1016/j.enfi.2018.10.004

    Factors related to limitation of life support within 48h of intensivecare unit admission: A multicenter study

    Blazquez V, Rodríguez A, Sandiumenge A, Oliver E, Cancio B, Ibañez M, MiróG, Navas E, Badía M, Bosque MD, Jurado MT, López M, Llauradó M, Masnou N, Pont T,Bodí M
    Med Intensiva

    DOI: 10.1016/j.medin.2018.03.010

    Big data and machine learning in critical care:Opportunities for collaborative research

    Organizing Committee of the Madrid 2017 Critical Care Datathon, Núñez ReizA, Martínez Sagasti F, Álvarez González M, Blesa Malpica A, Martín Benítez JC,Nieto Cabrera M, Del Pino Ramírez Á, Gil Perdomo JM, Prada Alonso J, Celi LA,Armengol de la Hoz MÁ, Deliberato R, Paik K, Pollard T, Raffa J, Torres F, Mayol J, Chafer J, González Ferrer A, Rey Á, González Luengo H, Fico G, Lombroni I,Hernandez L, López L, Merino B, Cabrera MF, Arredondo MT, Bodí M, Gómez J,Rodríguez A, Sánchez García M

    Med Intensiva

    DOI: 10.1016/j.medin.2018.06.002

    Positive-pressure needleless connectors did not increase rates of catheter hubcolonization respecting the use of neutral-pressure needleless connectors in aprospective randomized trial

    Delgado M, Capdevila JA, Sauca G, Méndez J, Rodriguez A, Yébenes JC; Sepsis,Inflammation, Safety Research Group (Gr-Sis, Agaur 2014-Sgr926)

    Enferm Infecc Microbiol Clin

    DOI: 10.1016/j.eimc.2019.07.012

    Interhospital Sepsis Code in Catalonia (Spain): Territorial model for initial care of patients with sepsis

    376: M, Lopez R, GranesA, Perez-Claveria V, Artigas A, Estany J; Comisión Asesora para la Atención alPaciente con Sepsis y Grup de Treball de Sèpsia i Xoc Sèptic (GTSiXS)SOCMIC-SOCMUE

    Med Intensiva

    DOI: 10.1016/j.medin.2019.05.008

    Prevalence and risk factorsfor Enterobacteriaceae in patients hospitalized with community-acquiredpneumonia

    Villafuerte D, Aliberti S, Soni NJ, Faverio P, Marcos PJ, Wunderink RG,Rodriguez A, Sibila O, Sanz F, Martin-Loeches I, Menzella F, Reyes LF, JankovicM, Spielmanns M, Restrepo MI; GLIMP Investigators

    Respirology

    DOI: 10.1111/resp.13663

    Nutritrauma: A Key Concept for Minimisingthe Harmful Effects of the Administration of Medical Nutrition Therapy

    Yébenes JC, Campins L, Martínez de Lagran I, Bordeje L, Lorencio C, Grau T, Montejo JC, Bodí M, Serra-Prat M; Working Group on Nutrition and Metabolism ofthe Spanish Society of Critical Care

    Nutrients

    DOI: 10.3390/nu11081775

    International prevalence and risk factorsevaluation for drug-resistant Streptococcus pneumoniae pneumonia

    Aliberti S, Cook GS, Babu BL, Reyes LF, H Rodriguez A, Sanz F, Soni NJ,Anzueto A, Faverio P, Sadud RF, Muhammad I, Prat C, Vendrell E, Neves J,Kaimakamis E, Feneley A, Swarnakar R, Franzetti F, Carugati M, Morosi M, Monge E,Restrepo MI; GLIMP investigators

    J Infect

    DOI: 10.1016/j.jinf.2019.07.004

    The association of cardiovascular failure withtreatment for ventilator-associated lower respiratory tract infection

    Martin-Loeches I, Torres A, Povoa P, Zampieri FG, Salluh J, Nseir S, Ferrer M,Rodriguez A; TAVeM study Group

    Intensive Care Med

    DOI: 10.1007/s00134-019-05797-6

    Basic critical care echocardiography training of intensivists allows reproducibleand reliable measurements of cardiac output

    Villavicencio C, Leache J, Marin J, Oliva I, Rodriguez A, Bodí M, Soni NJ

    Ultrasound J

    DOI: 10.1186/s13089-019-0120-0

    Sepsis-3: More specific is better?

    Rodríguez A

    Med Clin (Barc)

    DOI: 10.1016/j.medcli.2018.07.006

    In reply to «Veteran or novicein end-of-lifedecision-making in intensive care medicine? Promote ethicaldeliberation»

    Blazquez V, Rodríguez A, Sandiumenge A, Bodí M

    Med Intensiva

    DOI: 10.1016/j.medin.2019.10.010

  • Títol: Informacion, comunicacion y trabajo en equipo en medicina intensiva: Analisis Aleatorios de Seguridad en Tiempo Real relacionados con los sic y la traslacion conocmiento (AAESTRE-SIC)

    Òrgan finançador: Instituto de Salud Carlos III
    Any: 2016 – 2019

    Referència: PI16/00491

  • Títol: Daño miocardico en la neumonia neumococica grave como causa de mortalidad por eventos cardiovasculares agudos (NEUMOCAR)

    Òrgan finançador: Instituto de Salud Carlos III
    Any: 2017 – 2021

    Referència: PI16/00486

  • Title: Información, comunicación y trabajo en equipo en medicina intensiva: análisis aleatorios de seguridad en tiempo real realcionados con los SIC y la traslación conomimiento (AAESTRE-SIC) PI16/00491.

    Funding entity: Instituto de Salud Carlos III

    Duration: 2017 -2021

    Principal Investigator: María Bodí Saera

  • Title: 2017 SGR 00127 Suport a Grups de Recerca (SGR) IISPV-Fundació Salut (Consorci Sanitària del Maresme) Finançament- Grup de Recerca consolidat

    Funding entity: Ajuts SGR

    Duration: 2017 -2021

    Principal Investigator: María Bodí Saera

Membres De L’equip

  • Responsable de grup

    • Dra. María Bodí
    • Dr. Alejandro Rodriguez Oviedo
  • Investigadors Principals

    • Gonzalo Sirgo Luanco
    • Mónica Magret
  • Investigadors Clínics

    • Mari Carmen Gilabert
    • Federico Esteban Reboll
    • Ángel Pobo
    • Christian Villavicencio
    • Sara Rosich
    • Iban Oliva
    • Iulen Leache
    • Gerard Moreno
    • Vanessa Blázquez
    • Sandra Canelles
    • Oriol Plans
    • Manuel Samper
    • Paula Perello
    • Laura Claverias
    • Marc Cartanya
    • Raquel Carbonell
    • Frederic Gómez Bertomeu
    • Ester Picó
    • Ester Salvadó Geli
    • Alfonso Gedea Martin
  • Cintífics de dades

    • Manuel Ruíz
    • Jordi Albiol MsC
    • Eduard Mayol PhD
    • Josep Gómez
  • Coordinadora d'estudis

    • Sandra Trefler
  • Coordinadora Farmacia

    • Sonia Jornet
    • Laura Canadell
  • ICU- Farmacia

    • Xavier Teixido Huertas
    • Erika Esteve, Pitarch Pharm
  • Secretaria

    • Pilar Torné