Grup d’Investigació en Cardiologia Translacional i Clínica de Tarragona (INVESCART)

MALALTIES METABÒLIQUES I NUTRICIÓ
OBJECTIUS

El grup de recerca treballa en el camp de les malalties cardiovasculars, particularment, l’afectació isquèmica i insuficiència cardíaca. Els objectius són estudiar el valor diagnòstic i pronòstic de diversos biomarcadors en síndrome coronari agut i insuficiència cardíaca i el dany miocàrdic a Urgències.

RESPONSABLES
  • Dr. Alfredo Bardají

  • Dr. José Luís Ferreiro Gutiérrez

  • LÍNIES de recerca
  • MEMBRES DEL GRUP
  • Publicacions
  • Projectes
  • CONTACTE
  • Malalties cardiovasculars, el grup treballa en estudis clínics sobre cardiopatia isquèmica, insuficiència renal, insuficiència cardíaca i hipertensió.
  • Insuficiència cardíaca, el grup focalitza la seva activitat en l’estudi de marcadors clínics i biològics de mort sobtada.
  • El dany miocàrdic, el grup treballa en el perfil clínic i pronòstic, de l’infart de miocàrdic tipus 1, tipus 2, dany miocàrdic agut i dany miocàrdic crònic.
    Clinical characteristics and long-term prognosis of female patients with acute coronary syndrome

    Rocamora-Horrach M, Peiró ÓM, Bardají A, Flores-Benítez J, Ivorra-Cámara M, Carrasquer A, Ferreiro JL. Front Cardiovasc Med. 2024;11:1447533.

    DOI: 10.3389/fcvm.2024.1447533.
    2023

    Trajectories of Kidney Function in Heart Failure Over a 15-Year Follow-Up: Clinical Profiling and Mortality

    Zamora E, Codina P, Aimo A, Lupón J, Domingo M, Troya M, Santiago-Vacas E, Cediel G, Borrellas A, Ruiz-Cueto M, Romero-González GA, Santesmases J, Nuñez J, Bover J, Ara J, Bayes-Genis A. JACC Heart Fail. 2024;12:849-859.

    DOI: 10.1016/j.jchf.2024.01.004.

    Recovery of Left Ventricular Function and Long-Term Outcomes in Patients With Takotsubo Syndrome

    Almendro-Delia M, López-Flores L, Uribarri A, Vedia O, Blanco-Ponce E, López-Flores MDC, Rivas-García AP, Fernández-Cordón C, Sionis A, Martín-García AC, Vazirani R, Corbí-Pascual M, Salamanca J, Pérez-Castellanos A, Martínez-Sellés M, Becerra VM, Aritza-Conty D, López-País J, Guillén-Marzo M, Lluch-Requerey C, García-Rubira JC, Núñez-Gil IJ; RETAKO Investigators. J Am Coll Cardiol. 2024;84:1163-1174.

    DOI: 10.1016/j.jacc.2024.05.075.

    International Consensus Statement on Platelet Function and Genetic Testing in Percutaneous Coronary Intervention: 2024 Update

    Angiolillo DJ, Galli M, Alexopoulos D, Aradi D, Bhatt DL, Bonello L, Capodanno D, Cavallari LH, Collet JP, Cuisset T, Ferreiro JL, Franchi F, Geisler T, Gibson CM, Gorog DA, Gurbel PA, Jeong YH, Marcucci R, Siller-Matula JM, Mehran R, Neumann FJ, Pereira NL, Rizas KD, Rollini F, So DYF, Stone GW, Storey RF, Tantry US, Berg JT, Trenk D, Valgimigli M, Waksman R, Sibbing D. JACC Cardiovasc Interv. 2024;17:2639-2663.

    DOI: 10.1016/j.jcin.2024.08.027.

    P2Y12 Inhibitors in Chronic Coronary Syndromes Undergoing Elective PCI: Any Niche for Potent Agents?

    Ferreiro JL. JACC Cardiovasc Interv. 2024;17:371-373.

    DOI: 10.1016/j.jcin.2023.12.032.

    TCA cycle metabolites associated with adverse outcomes after acute coronary syndrome: mediating effect of renal function

    Sanchez-Gimenez R, Peiró ÓM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, et al. Front Cardiovasc Med. 2023 Jun 27;10:1157325.

    DOI: 10.3389/fcvm.2023.1157325.

    J-chronic total occlusion score predictive capacity for percutaneous coronary intervention success of chronic total occlusion: Results from a European single center cohort with progressive experience over time

    Mohandes M, Moreno C, Rojas S, Doblas V, Fuertes M, Fernández F, et al. Cardiol J. 2023;30(1):59-67.

    DOI: 10.5603/CJ.a2021.0058.

    Cardiac amyloidosis and left atrial appendage closure. The CAMYLAAC study

    Amat-Santos IJ, Delgado-Arana JR, Cruz-González I, Gutiérrez H, García-Bolao I, Millán X, Tirado-Conte G, Ruiz-Nodar JM, Mohandes M, Palazuelos J, Torres Saura F, Del Valle R, Valero Picher E, Núñez García JC, Gómez I, Albarrán Rincón R, Arzamendi D, Nombela-Franco L, Korniiko L, Barrero A, Santos-Martínez S, Serrador A, San Román JA. Rev Esp Cardiol (Engl Ed). 2023;76(7):503-510.

    DOI: 10.1016/j.rec.2022.08.001.

    Coronary angiography in patients without ST-segment elevation following out-of-hospital cardiac arrest

    Viana-Tejedor A, Andrea-Riba R, Scardino C, Ariza-Solé A, Bañeras J, García-García C, et al. Rev Esp Cardiol (Engl Ed). 2023;76(2):94-102.

    DOI: 10.1016/j.rec.2022.05.013.

    Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions

    Diego-Nieto A, Núñez JC, Miñana G, Amat-Santos IJ, Salinas-Sanguino P, Mohandes M, et al. Rev Esp Cardiol (Engl Ed). 2023;76(4):253-260.

    DOI: 10.1016/j.rec.2022.05.019.

    Performance of Coronary Angiography in the Detection of Coronary Artery Disease in Patients with Systolic Left Ventricular Dysfunction and No Prior Ischemic Heart Disease

    Peiró ÓM, Ferrero M, Romeu A, Carrasquer A, Bonet G, Mohandes M, Pernigotti A, Bardají A. J Clin Med. 2022 Feb 18;11(4):1097.

    DOI: 10.3390/jcm11041097. PMID: 35207370; PMCID: PMC8880097.

    Gut Microbiota-Derived Metabolites and Cardiovascular Disease Risk: A Systematic Review of Prospective Cohort Studies

    Sanchez-Gimenez R, Ahmed-Khodja W, Molina Y, Peiró OM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, Bardaji A, Papandreou C. Nutrients. 2022 Jun 27;14(13):2654

    DOI: 10.3390/nu14132654. PMID: 35807835; PMCID: PMC9268449.

    Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions

    Diego-Nieto A, Núñez JC, Miñana G, Amat-Santos IJ, Salinas-Sanguino P, Mohandes M, Regueiro A, Pan M, Lacunza J, Caballero-Borrego J, Fernández-Díaz JA, Fernández Cisnal A, Santos-Martínez S, Gonzalo N, Vaquerizo B, Rivero F, Jurado-Román A, Abellán-Huerta J, Rumiz González E, Rondán-Murillo J, López Benito M, Astorga Burgo JC, Jiménez Mazuecos J, Bosa Ojeda F, Moreno-Ambroj C, Sabaté M, Ojeda S, Valdesuso Aguilar R, López Pérez M, Sanchis J, Campo-Prieto A, Escaned J, Goicolea J, Martín-Moreiras J. Rev Esp Cardiol (Engl Ed). 2022 Jun 9:S1885-5857(22)00140-2. English, Spanish.

    DOI: 10.1016/j.rec.2022.05.019. Epub 2022 Jun 9. PMID: 35691552.

    Cardiac amyloidosis and left atrial appendage closure. The CAMYLAAC Study

    Amat-Santos IJ, Delgado-Arana JR, Cruz-González I, Gutiérrez H, García-Bolao I, Millán X, Tirado-Conte G, Ruiz-Nodar JM, Mohandes M, Palazuelos J, Torres Saura F, Del Valle R, Valero Picher E, Núñez García JC, Gómez I, Albarrán Rincón R, Arzamendi D, Nombela-Franco L, Korniiko L, Barrero A, Santos-Martínez S, Serrador A, San Román JA. Rev Esp Cardiol (Engl Ed). 2022 Aug 5:S1885-5857(22)00208-0. English, Spanish.

    DOI: 10.1016/j.rec.2022.08.001. Epub 2022 Aug 5. PMID: 35934294.

    Plasma trimethylamine-N-oxide, its precursors and risk of cardiovascular events in patients with acute coronary syndrome: Mediating effects of renal function

    Sanchez-Gimenez R, Peiró ÓM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, Papandreou C, Bardaji A. Front Cardiovasc Med. 2022 Sep 21;9:1000815.

    DOI: 10.3389/fcvm.2022.1000815. PMID: 36211587; PMCID: PMC9532606.

    Has the Fourth Universal Definition of Myocardial Infarction led to better diagnosis and risk stratification?

    Bueno H, Rossello X, Bardají A. Eur Heart J. 2021 Jul 8;42(26):2562-2564.

    DOI: 10.1093/eurheartj/ehaa486.

    Prognostic implications of myocardial injury in patients with and without COVID-19 infection treated in a university hospital

    Bardají A, Carrasquer A, Sánchez-Giménez R, Lal-Trehan N, Del-Moral-Ronda V, Peiró ÓM, Bonet G, Castilho G, Fort-Gallifa I, Benavent C, Recio G, Gutiérrez C, Villavicencio C, Auguet T, Boqué C. Rev Esp Cardiol (Engl Ed). 2021 Jan;74(1):24-32.

    DOI: 10.1016/j.rec.2020.08.027.

    Atrial fibrillation in patients with COVID-19. Usefulness of the CHA2DS2-VASc score: an analysis of the international HOPE COVID-19 registry

    Uribarri A, Núñez-Gil IJ, Aparisi Á, Arroyo-Espliguero R, Maroun Eid C, Romero R, Becerra-Muñoz VM, Feltes G, Molina M, García-Aguado M, Cerrato E, Capel-Astrua T, Alfonso-Rodríguez E, Castro-Mejía AF, Raposeiras-Roubín S, Espejo C, Pérez-Solé N, Bardají A, Marín F, Fabregat-Andrés Ó, D’ascenzo F, Santoro F, Akin I, Estrada V, Fernández-Ortiz A, Macaya C; en representación de los investigadores HOPE COVID-19. Rev Esp Cardiol. 2021 Jul;74(7):608-615. Spanish.

    DOI: 10.1016/j.recesp.2020.12.014.

    Clinical characteristics and prognostic implications of diabetes and myocardial injury in patients admitted to the emergency room

    Bonet G, Carrasquer A, Peiró ÓM, Sanchez-Gimenez R, Lal-Trehan N, Del-Moral-Ronda V, Fort-Gallifa I, Bardají A. BMC Cardiovasc Disord. 2021 Aug 30;21(1):414.

    DOI: 10.1186/s12872-021-02220-1. PMID: 34461832; PMCID: PMC8404360.

    New scoring system for predicting percutaneous coronary intervention of chronic total occlusion success: Impact of operator's experience

    Mohandes M, Moreno C, Fuertes M, Rojas S, Pernigotti A, Zambrano D, Doblas V, Fernández F, Guarinos J, Bardají A. Cardiol J. 2021 Sep 28.

    DOI: 10.5603/CJ.a2021.0109. Epub 2021 Sep 28. PMID: 34581426; PMCID: PMC10508064.

    Soluble urokinase plasminogen activator receptor as a long-term prognostic biomarker in acute coronary syndromes

    Peiro, Oscar Manuel; Cediel, German; Bonet, Gil; Rojas, Sergio; Quintern, Veronica; Carrasquer, Anna; Gonzalez-Del-Hoyo, Maribel; Sanz, Esther; Bardaji, Alfredo
    Biomarkers, 2020, vol. 25, p. 402-409

    DOI: 10.1080/1354750x.2020.1778090

    Metoprolol blunts the time-dependent progression of infarct size

    Lobo-Gonzalez M, Galán-Arriola C, Rossello X, González-Del-Hoyo M, Vilchez JP, Higuero-Verdejo MI, García-Ruiz JM, López-Martín GJ, Sánchez-González J, Oliver E, Pizarro G, Fuster V, Ibanez B
    Basic Res Cardiol. 2020 Aug 3;115(5):55

    DOI: 10.1007/s00395-020-0812-4

    Has the Fourth Universal Definition of Myocardial Infarction led to better diagnosis and risk stratification?

    Bueno H, Rossello X, Bardají A
    Eur Heart J. 2020 Jul 10;42(26):2562-2564

    DOI: 10.1093/eurheartj/ehaa486

    Comparative prediction of long-term mortality by the CHA2DS2-VASc score and cardiac troponin I levels in patients with atrial fibrillation at the emergency department

    González-Del-Hoyo M, Carrasquer A, Bonet G, Fort-Gallifa I, Bardají A
    Eur J Intern Med. 2020 Aug;78:154-156

    DOI: 10.1016/j.ejim.2020.04.021

    Impact of renal function on admission in COVID-19 patients: an analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID 19) Registry

    Uribarri A, Núñez-Gil IJ, Aparisi A, Becerra-Muñoz VM, Feltes G, Trabattoni D, Fernández-Rozas I, Viana-Llamas MC, Pepe M, Cerrato E, Capel-Astrua T, Romero R, Castro-Mejía AF, El-Battrawy I, López-País J, D’Ascenzo F, Fabregat-Andres O, Bardají A, Raposeiras-Roubin S, Marín F, Fernández-Ortiz A, Macaya C, Estrada V; HOPE COVID-19 Investigators
    J Nephrol. 2020 Aug;33(4):737-745

    DOI: 10.1007/s40620-020-00790-5

    Changes in causes of death and influence of therapeutic improvement over time in patients with heart failure and reduced ejection fraction

    Fernández-Vázquez D, Ferrero-Gregori A, Álvarez-García J, Gómez-Otero I, Vázquez R, Delgado Jiménez J, Worner Diz F, Bardají A, García-Pavía P, Bayés-Genís A, González-Juanatey JR, Cinca J, Pascual Figal DA
    Rev Esp Cardiol (Engl Ed). 2020 Jul;73(7):561-568

    DOI: 10.1016/j.rec.2019.09.030

    A single nucleotide deletion resulting in a frameshift in exon 4 of TAB2 is associated with a polyvalular syndrome

    Permanyer E, Laurie S, Blasco-Lucas A, Maldonado G, Amador-Catalan A, Ferrer-Curriu G, Fuste B, Perez ML, Gonzalez-Alujas T, Beltran S, Comas-Riu J, Bardají A, Evangelista A, Galiñanes M
    Eur J Med Genet. 2020 Apr;63(4):103854

    DOI: 10.1016/j.ejmg.2020.103854

    Percutaneous Left Atrial Appendage Closure in the Presence of Thrombus Using LAmbre Device and Cerebral Protection System

    Mohandes M, Pernigotti A, Morr CI, Bardají A
    Korean Circ J. 2020 Mar;50(3):281-283

    DOI: 10.4070/kcj.2019.0305

    Mortality risk assessment in Spain and Italy, insights of the HOPE COVID-19 registry

    Núñez-Gil IJ, Fernández-Pérez C, Estrada V, Becerra-Muñoz VM, El-Battrawy I, Uribarri A, Fernández-Rozas I, Feltes G, Viana-Llamas MC, Trabattoni D, López-País J, Pepe M, Romero R, Castro-Mejía AF, Cerrato E, Astrua TC, D’Ascenzo F, Fabregat-Andres O, Moreu J, Guerra F, Signes-Costa J, Marín F, Buosenso D, Bardají A, Raposeiras-Roubín S, Elola J, Molino Á, Gómez-Doblas JJ, Abumayyaleh M, Aparisi Á, Molina M, Guerri A, Arroyo-Espliguero R, Assanelli E, Mapelli M, García-Acuña JM, Brindicci G, Manzone E, Ortega-Armas ME, Bianco M, Trung CP, Núñez MJ, Castellanos-Lluch C, García-Vázquez E, Cabello-Clotet N, Jamhour-Chelh K, Tellez MJ, Fernández-Ortiz A, Macaya C; HOPE COVID-19 Investigators
    2020 Nov 9 [Epub ahead of print]. Intern Emerg Med

    DOI: 10.1007/s11739-020-02543-5

    Comorbidity burden and revascularization benefit in elderly patients with acute coronary syndrome

    Sanchis J, García Acuña JM, Raposeiras S, Barrabés JA, Cordero A, Martínez-Sellés M, Bardají A, Díez-Villanueva P, Marín F, Ruiz-Nodar JM, Vicente-Ibarra N, Alonso Salinas GL, Rigueiro P, Abu-Assi E, Formiga F, Núñez J, Núñez E, Ariza-Solé A
    2020 Aug 7 [Epub ahead of print]. Rev Esp Cardiol (Engl Ed).

    DOI: 10.1016/j.rec.2020.06.015

    Underlying heart diseases and acute COVID-19 outcomes.

    Núñez-Gil IJJ, Fernández-Ortiz A, Maroud Eid C, Huang J, Romero R, Becerra-Muñoz VM, Uribarri A, Feltes G, Trabatoni D, Fernandez-Rozas I, Viana-Llamas MC, Pepe M, Cerrato E, Bertaina M, Capel Astrua T, Alfonso E, Castro-Mejía AF, Raposeiras-Roubin S, D’Ascenzo F, Espejo Paeres C, Signes-Costa J, Bardaji A, Fernandez-Pérez C, Marin F, Fabregat-Andres O, Akin I, Estrada V, Macaya C.
    2020 Dec 21 [Epub ahead of print]. Cardiol J.

    DOI: 10.5603/CJ.a2020.0183

    Safety and efficacy of coronary laser ablation as an adjunctive therapy in percutaneous coronary intervention: a single-centre experience

    Mohandes M, Fernández L, Rojas S, Moreno C, Fuertes M, Fernández F, Pernigotti A, Gonzalez-Del-Hoyo M, Guarinos J, Sanz E, Bardají A
    2020 Nov 12 [Epub ahead of print]. Coron Artery Dis.

    DOI: 10.1097/MCA.0000000000000989

    Understanding the Adverse Hemodynamic Effects of Serious Thoracic Injuries During Cardiopulmonary Resuscitation: A Review and Approach Based on the Campbell Diagram

    Azeli, Youcef; Lorente Olazabal, Juan Victor; Monge Garcia, Manuel Ignacio; Bardaji, Alfredo
    Frontiers In Physiology, 2019, vol. 10, p. 1475

    DOI: 10.3389/fphys.2019.01475

  • Title: Implicación pronostica de la estructura y función cardiaca en el daño miocárdico no isquémico (PI19/00705)

    Funding entity: Instituto de Salud Carlos III

    Duration: 2020 – 2022

    Principal Investigator: Alfredo Bardají Ruiz, PhD

Membres De L’equip

  • Investigador/a Responsable

    • Dr. Alfredo Bardají
    • Dr. José Luís Ferreiro Gutiérrez
  • Investigador/a Sènior

    • Mohsen Mohandes Yusefian
    • Óscar Manuel Peiró Ibáñez
  • Investigador/a Postdoctoral

    • Anna Maria Carrasquer Cucarella
    • Esther Sanz Girgas
  • Doctorand/a

    • Gil Bonet Pineda
    • Sandra Cabrera Gómez
    • Ramón de Castro Aritméndiz
    • Marta Guillén Marzo
    • Gabriel Martín Sánchez
    • Judit Rodríguez López
    • Claudia Scardino
    • María Isabel Serrano Rodríguez
    • Luis Mauricio Torres Sánchez