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Tarragona Translational and Clinical Cardiology Research Group (INVESCART)

METABOLIC AND NUTRITION DISEASES
NUTRITION DIABETES OBESITY CHOLESTEROL
TARGETS

The research group works in the field of cardiovascular disease, particularly ischemic involvement and heart failure. The objectives are to study the diagnostic and prognostic value of various biomarkers in acute coronary syndrome and heart failure and myocardial damage in Emergencies.

RESPONSIBLE

  • Dr. Alfredo Bardají

  • José Luís Ferreiro Gutiérrez

  • RESEARCH LINES
  • GROUP MEMBERS
  • PUBLICATIONS
  • PROJECTS
  • CONTACT
  • Cardiovascular disease, the group is working on clinical studies on ischemic heart disease, kidney failure, heart failure and hypertension.
  • Heart failure, the group focuses its activity on the study of clinical and biological markers of sudden death.
  • Myocardial damage, the group is working on the clinical and prognostic profile, of type 1, type 2 myocardial infarction, acute myocardial damage and chronic myocardial damage.

    Year

    Trajectories of Kidney Function in Heart Failure Over a 15-Year Follow-Up: Clinical Profiling and Mortality

    Zamora E, Codina P, Aimo A, Lupón J, Domingo M, Troya M, Santiago-Vacas E, Cediel G, Borrellas A, Ruiz-Cueto M, Romero-González GA, Santesmases J, Nuñez J, Bover J, Ara J, Bayes-Genis A. JACC Heart Fail. 2024;12:849-859.

    DOI: 10.1016/j.jchf.2024.01.004.

    Recovery of Left Ventricular Function and Long-Term Outcomes in Patients With Takotsubo Syndrome

    Almendro-Delia M, López-Flores L, Uribarri A, Vedia O, Blanco-Ponce E, López-Flores MDC, Rivas-García AP, Fernández-Cordón C, Sionis A, Martín-García AC, Vazirani R, Corbí-Pascual M, Salamanca J, Pérez-Castellanos A, Martínez-Sellés M, Becerra VM, Aritza-Conty D, López-País J, Guillén-Marzo M, Lluch-Requerey C, García-Rubira JC, Núñez-Gil IJ; RETAKO Investigators. J Am Coll Cardiol. 2024;84:1163-1174.

    DOI: 10.1016/j.jacc.2024.05.075.

    International Consensus Statement on Platelet Function and Genetic Testing in Percutaneous Coronary Intervention: 2024 Update

    Angiolillo DJ, Galli M, Alexopoulos D, Aradi D, Bhatt DL, Bonello L, Capodanno D, Cavallari LH, Collet JP, Cuisset T, Ferreiro JL, Franchi F, Geisler T, Gibson CM, Gorog DA, Gurbel PA, Jeong YH, Marcucci R, Siller-Matula JM, Mehran R, Neumann FJ, Pereira NL, Rizas KD, Rollini F, So DYF, Stone GW, Storey RF, Tantry US, Berg JT, Trenk D, Valgimigli M, Waksman R, Sibbing D. JACC Cardiovasc Interv. 2024;17:2639-2663.

    DOI: 10.1016/j.jcin.2024.08.027.

    Cardiac amyloidosis and left atrial appendage closure. The CAMYLAAC study.

    Amat-Santos IJ, Delgado-Arana JR, Cruz-González I, Gutiérrez H, García-Bolao I, Millán X, Tirado-Conte G, Ruiz-Nodar JM, Mohandes M, Palazuelos J, Torres Saura F, Del Valle R, Valero Picher E, Núñez García JC, Gómez I, Albarrán Rincón R, Arzamendi D, Nombela-Franco L, Korniiko L, Barrero A, Santos-Martínez S, Serrador A, San Román JA. Rev Esp Cardiol (Engl Ed). 2023;76(7):503-510.

    DOI: 10.1016/j.rec.2022.08.001.

    Coronary angiography in patients without ST-segment elevation following out-of-hospital cardiac arrest. COUPE clinical trial

    Viana-Tejedor A, Andrea-Riba R, Scardino C, Ariza-Solé A, Bañeras J, García-García C, et al. Rev Esp Cardiol (Engl Ed). 2023;76(2):94-102.

    DOI: 10.1016/j.rec.2022.05.013.

    Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions

    Diego-Nieto A, Núñez JC, Miñana G, Amat-Santos IJ, Salinas-Sanguino P, Mohandes M, et al. Rev Esp Cardiol (Engl Ed). 2023;76(4):253-260.

    DOI: 10.1016/j.rec.2022.05.019.

    Cardiac amyloidosis and left atrial appendage closure. The CAMYLAAC study

    Amat-Santos IJ, Delgado-Arana JR, Cruz-González I, Gutiérrez H, García-Bolao I, Millán X, Tirado-Conte G, Ruiz-Nodar JM, Mohandes M, Palazuelos J, Torres Saura F, Del Valle R, Valero Picher E, Núñez García JC, Gómez I, Albarrán Rincón R, Arzamendi D, Nombela-Franco L, Korniiko L, Barrero A, Santos-Martínez S, Serrador A, San Román JA. Rev Esp Cardiol (Engl Ed). 2023;76(7):503-510.

    DOI: 10.1016/j.rec.2022.08.001.

    Coronary angiography in patients without ST-segment elevation following out-of-hospital cardiac arrest

    Viana-Tejedor A, Andrea-Riba R, Scardino C, Ariza-Solé A, Bañeras J, García-García C, et al. Rev Esp Cardiol (Engl Ed). 2023;76(2):94-102.

    DOI: 10.1016/j.rec.2022.05.013.

    TCA cycle metabolites associated with adverse outcomes after acute coronary syndrome: mediating effect of renal function

    Sanchez-Gimenez R, Peiró ÓM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, et al. Front Cardiovasc Med. 2023 Jun 27;10:1157325.

    DOI: 10.3389/fcvm.2023.1157325.

    J-chronic total occlusion score predictive capacity for percutaneous coronary intervention success of chronic total occlusion: Results from a European single center cohort with progressive experience over time

    Mohandes M, Moreno C, Rojas S, Doblas V, Fuertes M, Fernández F, et al. Cardiol J. 2023;30(1):59-67.

    DOI: 10.5603/CJ.a2021.0058.

    Performance of Coronary Angiography in the Detection of Coronary Artery Disease in Patients with Systolic Left Ventricular Dysfunction and No Prior Ischemic Heart Disease

    Peiró ÓM, Ferrero M, Romeu A, Carrasquer A, Bonet G, Mohandes M, Pernigotti A, Bardají A. J Clin Med. 2022 Feb 18;11(4):1097.

    DOI: 10.3390/jcm11041097. PMID: 35207370; PMCID: PMC8880097.

    Gut Microbiota-Derived Metabolites and Cardiovascular Disease Risk: A Systematic Review of Prospective Cohort Studies

    Sanchez-Gimenez R, Ahmed-Khodja W, Molina Y, Peiró OM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, Bardaji A, Papandreou C. Nutrients. 2022 Jun 27;14(13):2654

    DOI: 10.3390/nu14132654. PMID: 35807835; PMCID: PMC9268449.

    Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions

    Diego-Nieto A, Núñez JC, Miñana G, Amat-Santos IJ, Salinas-Sanguino P, Mohandes M, Regueiro A, Pan M, Lacunza J, Caballero-Borrego J, Fernández-Díaz JA, Fernández Cisnal A, Santos-Martínez S, Gonzalo N, Vaquerizo B, Rivero F, Jurado-Román A, Abellán-Huerta J, Rumiz González E, Rondán-Murillo J, López Benito M, Astorga Burgo JC, Jiménez Mazuecos J, Bosa Ojeda F, Moreno-Ambroj C, Sabaté M, Ojeda S, Valdesuso Aguilar R, López Pérez M, Sanchis J, Campo-Prieto A, Escaned J, Goicolea J, Martín-Moreiras J. Rev Esp Cardiol (Engl Ed). 2022 Jun 9:S1885-5857(22)00140-2. English, Spanish.

    DOI: 10.1016/j.rec.2022.05.019. Epub 2022 Jun 9. PMID: 35691552.

    Cardiac amyloidosis and left atrial appendage closure. The CAMYLAAC Study

    Amat-Santos IJ, Delgado-Arana JR, Cruz-González I, Gutiérrez H, García-Bolao I, Millán X, Tirado-Conte G, Ruiz-Nodar JM, Mohandes M, Palazuelos J, Torres Saura F, Del Valle R, Valero Picher E, Núñez García JC, Gómez I, Albarrán Rincón R, Arzamendi D, Nombela-Franco L, Korniiko L, Barrero A, Santos-Martínez S, Serrador A, San Román JA. Rev Esp Cardiol (Engl Ed). 2022 Aug 5:S1885-5857(22)00208-0. English, Spanish.

    DOI: 10.1016/j.rec.2022.08.001. Epub 2022 Aug 5. PMID: 35934294.

    Plasma trimethylamine-N-oxide, its precursors and risk of cardiovascular events in patients with acute coronary syndrome: Mediating effects of renal function

    Sanchez-Gimenez R, Peiró ÓM, Bonet G, Carrasquer A, Fragkiadakis GA, Bulló M, Papandreou C, Bardaji A. Front Cardiovasc Med. 2022 Sep 21;9:1000815.

    DOI: 10.3389/fcvm.2022.1000815. PMID: 36211587; PMCID: PMC9532606.

    Has the Fourth Universal Definition of Myocardial Infarction led to better diagnosis and risk stratification?

    Bueno H, Rossello X, Bardají A. Eur Heart J. 2021 Jul 8;42(26):2562-2564.

    DOI: 10.1093/eurheartj/ehaa486.

    Prognostic implications of myocardial injury in patients with and without COVID-19 infection treated in a university hospital

    Bardají A, Carrasquer A, Sánchez-Giménez R, Lal-Trehan N, Del-Moral-Ronda V, Peiró ÓM, Bonet G, Castilho G, Fort-Gallifa I, Benavent C, Recio G, Gutiérrez C, Villavicencio C, Auguet T, Boqué C. Rev Esp Cardiol (Engl Ed). 2021 Jan;74(1):24-32.

    DOI: 10.1016/j.rec.2020.08.027.

    Atrial fibrillation in patients with COVID-19. Usefulness of the CHA2DS2-VASc score: an analysis of the international HOPE COVID-19 registry

    Uribarri A, Núñez-Gil IJ, Aparisi Á, Arroyo-Espliguero R, Maroun Eid C, Romero R, Becerra-Muñoz VM, Feltes G, Molina M, García-Aguado M, Cerrato E, Capel-Astrua T, Alfonso-Rodríguez E, Castro-Mejía AF, Raposeiras-Roubín S, Espejo C, Pérez-Solé N, Bardají A, Marín F, Fabregat-Andrés Ó, D’ascenzo F, Santoro F, Akin I, Estrada V, Fernández-Ortiz A, Macaya C; en representación de los investigadores HOPE COVID-19. Rev Esp Cardiol. 2021 Jul;74(7):608-615. Spanish.

    DOI: 10.1016/j.recesp.2020.12.014.

    Clinical characteristics and prognostic implications of diabetes and myocardial injury in patients admitted to the emergency room

    Bonet G, Carrasquer A, Peiró ÓM, Sanchez-Gimenez R, Lal-Trehan N, Del-Moral-Ronda V, Fort-Gallifa I, Bardají A. BMC Cardiovasc Disord. 2021 Aug 30;21(1):414.

    DOI: 10.1186/s12872-021-02220-1. PMID: 34461832; PMCID: PMC8404360.

    New scoring system for predicting percutaneous coronary intervention of chronic total occlusion success: Impact of operator's experience

    Mohandes M, Moreno C, Fuertes M, Rojas S, Pernigotti A, Zambrano D, Doblas V, Fernández F, Guarinos J, Bardají A. Cardiol J. 2021 Sep 28.

    DOI: 10.5603/CJ.a2021.0109. Epub 2021 Sep 28. PMID: 34581426; PMCID: PMC10508064.

    Understanding the Adverse Hemodynamic Effects of Serious Thoracic Injuries During Cardiopulmonary Resuscitation: A Review and Approach Based on the Campbell Diagram

    Azeli, Youcef; Lorente Olazabal, Juan Victor; Monge Garcia, Manuel Ignacio; Bardaji, Alfredo
    Frontiers In Physiology, 2019, vol. 10, p. 1475

    DOI: 10.3389/fphys.2019.01475

    Safety and feasibility of transradial access for percutaneous coronary intervention in chronic total occlusions

    Diego-Nieto A, Núñez JC, Miñana G, Amat-Santos IJ, Salinas-Sanguino P, Mohandes M, et al. Rev Esp Cardiol (Engl Ed). 2023;76(4):253-260.

    DOI: 10.1016/j.rec.2022.05.019.

  • Title: Implicación pronostica de la estructura y función cardiaca en el daño miocárdico no isquémico (PI19/00705)

    Funding entity: Instituto de Salud Carlos III

    Duration: 2020 – 2022

    Principal Investigator: Alfredo Bardají Ruiz, PhD

Team Members

  • Responsible Researcher

    • Dr. Alfredo Bardají
    • José Luís Ferreiro Gutiérrez

  • Senior Researcher

    • Mohsen Mohandes Yusefian
    • Óscar Manuel Peiró Ibáñez

  • Postdoctoral Researcher

    • Anna Maria Carrasquer Cucarella
    • Esther Sanz Girgas

  • PhD Student

    • Gil Bonet Pineda
    • Sandra Cabrera Gómez
    • Ramón de Castro Aritméndiz
    • Marta Guillén Marzo
    • Gabriel Martín Sánchez
    • Judit Rodríguez López
    • Claudia Scardino
    • María Isabel Serrano Rodríguez
    • Luis Mauricio Torres Sánchez

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