In Spain, 17,241 sudden cardiac deaths are recorded every year

The incidence of sudden cardiac death (SCD) in the Mediterranean area is one third lower than in countries in northern Europe and America. This is the conclusion of a study co‑led by the Pere Virgili Health Research Institute (IISPV) and the Catalan Medical Emergency System (SEM), with the participation of the Institute of Legal Medicine and Forensic Sciences of Catalonia (IMLCFC), Joan XXIII University Hospital of Tarragona, Sant Joan University Hospital of Reus, Xarxa Santa Tecla, IDIAP Jordi Gol, Rovira i Virgili University, and the Catalan Health Institute. The study, recently published in the international journal BMJ Global Health, analyses the factors that explain the lower impact of sudden cardiac death in the Mediterranean region.

According to the study (Epidemiology of sudden cardiac arrest in the western Mediterranean area based on a prospective registry), 70% of sudden deaths are caused by cardiac conditions. Chronic coronary disease is identified as the main cause of sudden death, followed by acute coronary disease and cardiomyopathies. In addition, 15% of sudden deaths are due to non‑cardiac cardiovascular causes, such as pulmonary thromboembolism or intracranial haemorrhage. The remaining 15% are related to non‑cardiovascular causes, such as digestive bleeding or infections. Alfredo Bardají, cardiologist at Joan XXIII University Hospital, highlights that “this study found that acute myocardial infarction as a cause of sudden cardiac death is decreasing, thanks to improvements in early treatment”.

Regarding the possible prevention of sudden death, Youcef Azeli, principal investigator of the study, SEM doctor, physician at Sant Joan University Hospital of Reus and head of the IISPV research group in emergencies, explains that “only one third of patients have a previous history of heart disease, which makes prediction difficult. Also, in 50% of cases, cardiac arrest occurs without previous symptoms, which makes treatment harder”. Even so, the study shows that one in five patients had a medical consultation in the four weeks before the event, which highlights the need to work on medium‑term prevention strategies to improve the detection of patients at risk.

This research is also relevant for two additional reasons. First, it involved up to six institutions, which made it possible to gather information from many different sources. In this regard, the participation of the Institute of Legal Medicine and Forensic Sciences of Catalonia (IMLCFC), part of the Department of Justice and Democratic Quality, is especially important. Its director, Eneko Barbería, points out that “including forensic analyses and data allows us to obtain a complete picture of sudden cardiac death and makes this study unique in the Mediterranean area and in Europe”.

Second, this is the first study that provides real data on the incidence of sudden death in Catalonia and Spain, thanks to the wide participation of institutions that contributed information. According to the Catalonia Cardiac Arrest and Sudden Death Registry (RAIMCAT), 2,700 cases are recorded every year in Catalonia and initially attended by SEM, which means 7 cases per day. In Spain as a whole, the annual number is 17,241 cases, or 47 cases per day. This study, unique in Europe, shows that sudden cardiac death is one of the most important causes of death in Spain, just after lung cancer.

The survival rate after sudden cardiac arrest is only 10%. Cases with previous chest pain or where an automated external defibrillator (AED) is used before SEM arrives have a better chance of survival. For this reason, in the presence of warning signs such as chest pain, or when witnessing a sudden loss of consciousness, it is essential to recognise the situation quickly, start high‑quality chest compressions, and use an AED as soon as possible.

This study, funded by the Catalan Resuscitation Council (CCR), has made it possible to identify the cause of death in a higher percentage of cases than other published studies. Research like this, with high‑quality registries on sudden cardiac death, helps advance precision medicine, prevention, and treatments that improve patient care.

Reference: Azeli, Y., Barbería, E., Solà-Muñoz, S., Landín, I., Fernández, A., Rey-Reñones, C., García-Gual, C., Gomez-Tortosa, A., Granado-Font, E., Fernandez-Sender, L., García-Vilana, S., Bonet, G., Jimènez-Fàbrega, X., & Bardaji, A. (2025). Epidemiology of sudden cardiac arrest in the western Mediterranean area based on a prospective registry. BMJ global health, 10(11), e020462. https://doi.org/10.1136/bmjgh-2025-020462

This tool gathers detailed nutritional information on 850 products from 42 brands available in the main supermarkets in Spain. Its aim is to provide dietetics, nutrition, paediatrics and other health professionals with a reliable and updated source of information about the composition of these foods. This allows them to accurately assess nutrition during the first years of life and offer recommendations that promote a healthier and more sustainable diet. In addition, the results can serve as a basis for designing more effective food and regulatory policies.

According to Nancy Babio, researcher at the Human Nutrition Unit of the URV and coordinator of the project, “this database is a key step to provide health professionals with objective and evidence‑based information, in a context where the offer of commercial products for young children is growing quickly and does not always follow public health criteria”.

The results of the analysis, published in the scientific journal European Journal of Pediatrics, show worrying data. Besides confirming that only 20% of the products analysed meet all the nutritional profile and advertising criteria recommended by the WHO, it also warns that 60% of the food contains excessive amounts of sugar, and 99% of fruit purées would require a “high in sugar” warning label. In fact, none of the foods analysed should be advertised according to WHO guidelines.

The analysis also shows that 30% of the products include added sugars or sweeteners, such as honey or concentrated juices, and that none of the products meet all the WHO criteria for commercial promotion. Moreover, 98% display unauthorised claims or promotional messages.

“These results highlight the urgent need to improve regulation, both in the formulation and in the advertising of foods aimed at young children. At the moment, this is governed by a co‑regulation code (PAOS) that is not legally binding and has not worked as expected,” warns Roser Martí, president of CODINUCAT.

The Baby & Toddler Food Composition Database – InfantBase is a tool designed both for professional use and for political decision‑making.

This tool is part of the PRINUT project (Early Childhood: Nutritional Analysis and Regulation of Commercial Foods), which is aligned with public health strategies aimed at promoting healthy and safe eating during early childhood, following WHO recommendations and the PAAS (Comprehensive Plan for Health Promotion through Physical Activity and Healthy Eating) of the Government of Catalonia.

“As scientists and health professionals, we believe we have the responsibility to translate scientific evidence into effective policies that protect children’s health. We hope to receive institutional support to move forward in this direction,” concludes Babio.

The GEMMAIR research group received the Joan Pedrerol Gallego Award for the Social Impact of Research from the Social Council of the Universitat Rovira i Virgili last Thursday, 6 November. The award corresponds to the 2025 edition, in the field of health and life sciences, ex ante category.

The winning project, titled “Bisphenol A and liver health: Impact of a BPA‑free diet on Metabolic Dysfunction‑Associated Steatotic Liver Disease”, was presented by researchers Maria Teresa Auguet Quintillà, Helena Clavero Mestres, Carmen Aguilar Crespillo, José Antonio Porras, David Riesco, Salomé Martínez, Margarita Vives and Fàtima Sabench Pereferrer.

Succipro, a spin-off created in 2022 as a result of research from IRB CatSud (the new name that the current IISPV will adopt from 2026), has joined the business and innovation platform Catalonia.health. This step will help the company connect with other organisations in the Catalan biomedical sector, create synergies, share knowledge and speed up the development of its products.

Succipro focuses on developing new therapeutic strategies based on succinate modulation, with the aim of addressing inflammatory and metabolic diseases that affect millions of people. All of this is explained in this video.

At the moment, Succipro is developing a drug for the treatment of Inflammatory Bowel Disease (IBD). It is currently in the preclinical phase and shows very promising initial results. Succipro’s drugs also have the potential to treat other complex diseases of high clinical relevance, such as diabetes or certain types of cancer, where inflammation and metabolism play an important role.

At Succipro, the team works every day to improve the quality of life of people living with these conditions. The company is strongly committed to developing therapies that address real and personalised problems in patients. This approach follows the principles of personalised medicine, designing molecules with proper scientific and methodological validation to solve problems that are not yet fully addressed.

For Succipro, joining Catalonia.health is a “strategic decision that will allow the company to build connections with other organisations in the Catalan biomedical sector”. This collaboration is expected to help create synergies, share knowledge and accelerate the development of its products. This link between science, business and health is seen as essential to position Catalonia as an international reference in biomedicine.

More information: https://www.succipro.com/ https://www.iispv.cat/

The project is supported by the Diputació de Tarragona, which has granted funding of 100,000 euros to carry out the initiative

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The Pere Virgili Health Research Institute (IISPV) — which from 2026 will become the Southern Catalonia Biomedical Research Institute (IRB CatSud) — is leading the XISS project to integrate biomedical research and social innovation. The aim of the project is to transform the province’s healthcare system by creating effective connections between biomedical research, technological innovation, and citizen participation, with a direct impact on people’s health and well‑being. This initiative is carried out with the collaboration of the Diputació de Tarragona, which has provided a grant of €100,000 to support its development.

The project has enabled the preliminary studies for the creation of the Southern Catalonia Clinical Research Unit (UiC), which will be located at Sant Joan University Hospital in Reus and coordinated together with the three health regions (Camp de Tarragona, Terres de l’Ebre, and Baix Penedès). This infrastructure will make it possible to develop advanced clinical trials, including phase I oncology studies, as well as multicentre research on cardiovascular, metabolic, infectious, and neurodegenerative diseases.

The UiC will make it easier for patients from rural or geographically dispersed areas to take part in studies, reducing inequalities and increasing access to therapeutic innovation. In addition, data interoperability and the implementation of telemedicine services will ensure equal opportunities in access to clinical trials.

Territorial and social impact

The project covers 184 municipalities and 10 counties in the province of Tarragona, involving local and socioeconomic stakeholders (city councils, hospitals, primary care centres, the university, civil society, patient associations, biotechnology and pharmaceutical companies, business clusters, and start‑ups).

Among the results already achieved are:

A response to inequalities

An analysis of the Spanish Clinical Studies Registry shows that the province of Tarragona has a much lower concentration of clinical trials than Barcelona (21.89 per million inhabitants compared to 114.89). The XISS project addresses this need by ensuring a more balanced distribution of resources and clinical research structures across Catalonia.

The XISS project positions itself as a national reference in translating scientific knowledge into clinical practice, promoting a healthcare system focused on people, the territory, and the reduction of social and geographical inequalities.

The Infection and Immunity Research Group (INIM) of IISPV has participated in a project awarded in the 2025 Health Research Call of “La Caixa” Foundation. The project belongs to the area of infectious diseases and focuses on the study of HIV virological control. It is coordinated by Dr. Ezequiel Ruiz-Mateos from IBiS (Seville) and involves four research groups in total, which have received a grant of €999,952.40.

The award ceremony took place on November 20 at CosmoCaixa in Barcelona, where Anna Rull attended as Principal Investigator of the INIM group at IISPV. The group also highlighted the participation of the Infectious Diseases Unit of Hospital Joan XXIII.

Researcher Noelia Ramírez from IISPV took part on November 28 in the Eurecat Reus symposium on epigenetic and metabolic interactions

The researcher from the Pere Virgili Health Research Institute (IISPV), Noelia Ramírez, participated in the 3rd Eurecat Symposium on Epigenetic and Metabolic Interactions, held on November 28 at Eurecat’s headquarters in Reus. Her presentation was part of a talk entitled “Advancing Precision Environmental Health: From comprehensive exposure characterisation to metabolic and epigenetic markers of effect.”

In her conclusions, she explained that environmental exposures are dynamic, come from multiple sources, and are biologically complex. “To address their impact on health, we need integrated and high-resolution approaches that combine chemistry, biology, and data science,” Ramírez said.

She added that the paradigm of Precision Environmental Health integrates “a detailed characterisation of exposure with the evaluation of effects through omics sciences, in order to reveal how specific environmental mixtures influence molecular pathways, identify early biomarkers of susceptibility, and guide more effective prevention strategies.”

An escape room, medical tests and cardiopulmonary resuscitation workshops made the work of IISPV visible. The Servei d’Emergències Mèdiques Generalitat, Ajuntament de Tarragona and the Markets of Tarragona joined the initiative held in the city centre.

Around 450 people took part this Saturday, 22 November, in the city centre of Tarragona in the event ‘La recerca en salut surt al carrer’, organised by Institut d’Investigació Sanitària Pere Virgili (IISPV) as part of its 20th anniversary. Throughout the morning, dozens of people participated continuously in the activities, which were open to everyone. The main goal was to bring citizens closer to the work carried out by the Institute in the region.

Plaça Corsini and the Mercat Central became a large laboratory and a space for scientific outreach, where activities —an escape room, medical tests and resuscitation workshops with a visit to an ambulance— attracted people of all ages.

The escape room ‘Investigate and… help us!’ caught the attention of about 70 people. The medical tests ‘Here we take care of you!’, located inside the Market, worked without interruption, serving up to 100 people. Participants underwent early screenings for diabetes and prediabetes, blood pressure measurements to assess cardiovascular risk, and body composition analysis tests.

As for the cardiopulmonary resuscitation workshops ‘Get motivated and resuscitate!’, they involved professionals from IISPV and the Servei d’Emergències Mèdiques (SEM) of the Generalitat, who carried out simulations with mannequins in the square, teaching how to identify a cardiac arrest and perform intervention manoeuvres. In addition, citizens had the chance to see an SEM ambulance up close, which was displayed in the same square. Around 280 people took part in this activity.

The organisation of the event was supported by the SEM of Generalitat, the Ajuntament de Tarragona and the Mercats de Tarragona.

These microorganisms are essential for the product to meet the international definition of kefir established by WHO and FAO.

Around 80% of the products labelled as “kefir” in Spain do not provide information about the presence of yeasts. These microorganisms are necessary for the product to meet the international definition of kefir set by the Codex Alimentarius, prepared jointly by the World Health Organization (WHO) and the Food and Agriculture Organization (FAO). This is the conclusion of a study led by a research team from the Department of Biochemistry and Biotechnology of the Universitat Rovira i Virgili and the Pere Virgili Health Research Institute (IISPV), presented at the latest congress of the Spanish Federation of Nutrition, Food and Dietetic Societies.

Kefir is a fermented dairy food that differs from other similar products, such as yogurt, because of its mixed fermentation, which is the result of the combined action of lactic acid bacteria, acetic acid bacteria and yeasts. In the study, carried out in the summer of 2025, products labelled as “kefir” were analysed in the main supermarkets of the country, selected according to the market share report of Kantar Worldpanel, which includes national and regional chains and covers more than 56.7% of the market. The labelling of 170 drinkable and spoonable kefirs was evaluated, paying special attention to the explicit declaration of yeasts.

The results showed a great variability in the information provided by manufacturers, which, according to the research team, may cause confusion among consumers and make it difficult to correctly identify the product according to international standards. “In many cases, the name ‘kefir’ is used as a commercial claim, even though the products do not meet the international definition, which requires the presence of yeasts,” explain Lucía Iglesias-Vázquez and Nadine Khoury, researchers of the study.

The authors warn that the current European regulation on food information does not require declaring the presence of microorganisms on food labels. Moreover, in some fermented dairy products it even allows the omission of the list of ingredients, which may reduce transparency and contribute to the trivialisation of a food like kefir, which offers many health benefits.

Faced with this situation, the research team suggests that the industry should adopt clearer and more consistent labelling practices, such as explicitly indicating the presence of bacteria and yeasts. “Moving towards a harmonised European regulation that sets minimum microbiological criteria would be essential to protect the authenticity of kefir and strengthen consumer confidence through a clear list of ingredients,” say Nancy Babio and Jordi Salas, professors and researchers from the Department of Biochemistry and Biotechnology of URV, IISPV and CIBEROBN.

The initiative aims to raise public awareness of the importance of acquiring healthy lifestyle habits and supporting biomedical research carried out in the territory
The town councils of Perafort and Puigdelfí and of Els Garidells are organizing the 10th edition of the Solidarity Walk ‘Let’s Take a Step Against Diabetes’, which will take place next Sunday, November 23rd. This is a well-established event that returns this year full of symbolism and solidarity. This edition will be especially meaningful, as the 10 years of the walk coincide with the 20th anniversary of the Institut d’Investigació Sanitària Pere Virgili (IISPV), the center that will receive the funds raised during the event. Over these 10 editions, the organizing councils have managed to raise a total of €11,000, which has been used to support diabetes research projects carried out by the Institute.

The Solidarity Walk ‘Let’s Take a Step Against Diabetes’ aims to raise awareness among the population about the importance of adopting healthy lifestyle habits and to support biomedical research carried out in the region. All the funds raised will go to the Diabetes and Associated Metabolic Diseases Research Group (DIAMET) at IISPV, which focuses on finding new knowledge and strategies to improve the prevention, diagnosis, and treatment of diabetes and other metabolic diseases.

“The Perafort Town Council reaffirms its commitment to health, solidarity, and medical research through this initiative—values we consider essential for the well-being of our citizens. The funds are allocated to the IISPV to support research and scientific progress in this field,” said the mayor of Perafort, Joan Martí Pla i Pla. The Perafort Town Council thanks all the individuals and organizations involved and invites everyone to join this solidarity cause. Taking a step against diabetes is taking a step for everyone’s health.

There are different types of diabetes, but the most common are type 1 and type 2. Type 1 diabetes affects about 0.2% of the population in Spain, and around 10% of diagnosed cases are in young people and children. Type 2 diabetes affects between 6% and 14% of the population. This percentage depends on the age group considered, but the older the person, the higher the incidence.

The director of the IISPV, Joan Vendrell, explains that “diabetes is not visible, but it can be controlled with information and a healthy lifestyle. In this sense, events like the walk are very valuable, as they help raise awareness about the disease and its impact, and also promote the work we do. Moreover, they are an opportunity for people to contribute to the development of the various research projects underway at the Institute.”

With a registration fee of €5, participants will receive a commemorative T-shirt, enjoy breakfast and drinks in Els Garidells, and take part in a raffle of products offered by the event’s sponsors after the walk. Registration is open until November 21st, 2025, through the following link: https://serveis.iispv.cat/events/desena-caminada-contra-la-diabetis